IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation and active when dephosphorylated at

and active when dephosphorylated at this site

Transcription of this gene is highly inducible in response to many cytokines and hormones

Maternal plasma CRH probably originates from the placenta

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

isolated 8

IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation and active when dephosphorylated atThis gene encodes a member of the p47 immunity related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.