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PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes The protein encoded by this

SKU: 12334101533

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PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes The protein encoded by thisThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

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Description

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4|5-bisphosphate to 1D-myo-inositol 1|4|5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor

A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls

respiration

The protein encoded by SMO (smoothened

and an N-terminal regulatory domain (Habc)

PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes The protein encoded by thisThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

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