Histone H2A.X(Phospho Ser139) Polyclonal Antibody, 20ul[BT-AP09928] Protein Research The protein encoded by this

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA

thus may function in signaling pathways utilized broadly during fetal development

The encoded protein functions in mRNA processing

Regulates the circadian expression of the core clock components NR1D1 and ARNTL/BMAL1

Overexpression of CDCA7 is found to enhance the transformation of lymphoblastoid cells

Histone H2A.X(Phospho Ser139) Polyclonal Antibody, 20ul[BT-AP09928] Protein Research The protein encoded by thisHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This