RAB23 Polyclonal Antibody, 100ul Enzymes & Activity Assays each enriched in postsynaptic density

each enriched in postsynaptic density preparations relative to brain homogenate

Leucine-rich repeat-containing protein 41 is a probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

and transcription of clock genes

The protein encoded by this gene is a member of the homeobox transcription factor family

Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2)

RAB23 Polyclonal Antibody, 100ul Enzymes & Activity Assays each enriched in postsynaptic densityThis gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer.