PKN Polyclonal Antibody, 100ul Serum Mutations in this gene are

Mutations in this gene are a cause of spastic ataxia 2

The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities

Deficiency in this protein (B-cell linker)has also been shown in some cases of pre-B acute lymphoblastic leukemia

MMP7 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs)

Through a phosphatidylinositol-calcium second messenger system

PKN Polyclonal Antibody, 100ul Serum Mutations in this gene areThe protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The