TRIM27 Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations and deletions at this

Mutations and deletions at this locus have been associated with severe mental retardation

and protein kinase C in vitro

exons 2 and 3 encode the alpha1 and alpha2 domain

An important paralog of this gene is LSAMP

The protein encoded by VIP (vasoactive intestinal peptide) belongs to the glucagon family

TRIM27 Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations and deletions at thisThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N terminus of this protein with the truncated C