CDC37(Phospho-Ser13) Rabbit Polyclonal Antibody, 50ul Immunoassays suggesting a cell cycle function

suggesting a cell cycle function

Uracil bases occur from cytosine deamination or misincorporation of dUMP residues

Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor

This gene is present in a gene cluster on chromosome 11

and murine studies suggest a role in tumor-associated tissue remodeling

CDC37(Phospho-Ser13) Rabbit Polyclonal Antibody, 50ul Immunoassays suggesting a cell cycle functionThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.