TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube This gene encodes a secreted

This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes

The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form

Nuclear receptor subfamily 3 group C member 1 is typically found in the cytoplasm

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

The nuclear transport factor 2 is required for nuclear import of the small Ras-like GTPase

TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube This gene encodes a secretedTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as