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MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System It encodes a heparin-binding protein

SKU: 1789362289

4.2
USD162.00 USD182.00

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MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System It encodes a heparin-binding proteinMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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Description

It encodes a heparin-binding protein

This gene encodes a member of the glycosyltransferase 2 protein family

It acts as a decoy receptor that competes with death receptors for ligand binding

calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR)

The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype

MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System It encodes a heparin-binding proteinMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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