Fhit(Phospho Tyr114) Polyclonal Antibody, 100ul Peptide Modification Loss of function or expression

Loss of function or expression of this gene has been detected in multiple tumors

This gene is a member of the junctophilin gene family

Two transcript variants encoding different isoforms have been found for EHHADH

The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse

This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion

Fhit(Phospho Tyr114) Polyclonal Antibody, 100ul Peptide Modification Loss of function or expressionThis gene, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively