Phospho-c-Abl (Y245) Polyclonal Antibody, 100ul Antibodies This gene lies in close

This gene lies in close proximity to thymidylate synthase gene on chromosome 18

Clear graduation lines facilitate easy observation

Alternative splicing results in multiple transcripts encoding different isoforms

At least five transcript variants encoding five different isoforms have been found for this gene

FDA registered company (registration No

Phospho-c-Abl (Y245) Polyclonal Antibody, 100ul Antibodies This gene lies in closeABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation, suggesting a