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KGP1 Polyclonal Antibody, 100ul Polyclonal Antibodies Several alternatively spliced transcript variants

SKU: 2319285225

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KGP1 Polyclonal Antibody, 100ul Polyclonal Antibodies Several alternatively spliced transcript variantsMammals have three different isoforms of cyclic GMP dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2,

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Description

Several alternatively spliced transcript variants have been identified from this gene

The variation of this locus may affect the development of alcohol-related problems

Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome

Mediates AURKA localization to spindle microtubules

This protein is localized to the trans Golgi network

KGP1 Polyclonal Antibody, 100ul Polyclonal Antibodies Several alternatively spliced transcript variantsMammals have three different isoforms of cyclic GMP dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2,

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