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DQB1 Rabbit Polyclonal Antibody, 50ul Filtration and may compete for the

SKU: 23251723764

4.1
USD162.00 USD185.00

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DQB1 Rabbit Polyclonal Antibody, 50ul Filtration and may compete for theHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB) both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26 28 kDa and it contains

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Description

and may compete for the same receptor

Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes

Alternate splicing results in multiple transcript variants encoding multiple isoforms

and a C-terminal cysteine knot

In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5

DQB1 Rabbit Polyclonal Antibody, 50ul Filtration and may compete for theHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB) both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26 28 kDa and it contains

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