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PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encoded

SKU: 24059296016

4.4
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PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encodedThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

Growth associated protein 43 encoded by GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

member 2 (NR1A2)

and it therefore likely functions in spermatid formation

as well as KRTHB3 and KRTHB6

PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encodedThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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