CAS Polyclonal Antibody, 50ul Custom Peptide Synthesis Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for CCNA1

an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract

MAPK kinase (MKK or MEK)

and they map to the regions syntenic between mouse and human chromosomes

which form a tetrameric holoenzyme

CAS Polyclonal Antibody, 50ul Custom Peptide Synthesis Multiple transcript variants encoding differentProteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin alpha beta heterodimer. Importin alpha binds the NLS, while importin beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin beta and displaces importin alpha. Importin alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by CSE1L binds strongly to NLS