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ASAP2 Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Two related serine/threonine kinases

SKU: 25721471616

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ASAP2 Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Two related serine/threonine kinasesThis gene encodes a multidomain protein containing an N terminal alpha helical region with a coiled coil motif, followed by a pleckstrin homology (PH) domain, an Arf GAP domain, an ankyrin homology region, a proline rich region, and a C terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2 beta (PYK2). The encoded protein forms a stable complex

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Description

Two related serine/threonine kinases

It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA

The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form

this protein is predominantly expressed in the sebaceous gland of the skin

ASAP2 Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Two related serine/threonine kinasesThis gene encodes a multidomain protein containing an N terminal alpha helical region with a coiled coil motif, followed by a pleckstrin homology (PH) domain, an Arf GAP domain, an ankyrin homology region, a proline rich region, and a C terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2 beta (PYK2). The encoded protein forms a stable complex

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