PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification The encoded protein plays a

The encoded protein plays a role in many cellular processes including cell cycle progression

This protein| along with TAB1 and MAP3K7| also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK)| which may regulate the development and function of osteoclasts

This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP)| and controls a variety of cell functions including transcription regulation and apoptosis

This gene encodes a subunit of a tRNA-specific adenosine deaminase

It is the vertebrate homologue of the yeast protein Mex67p

PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification The encoded protein plays aThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in