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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a protein

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a proteinLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

This gene encodes a protein containing an alpha/beta hydrolase fold| which is a catalytic domain found in a very wide range of enzymes

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance

This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

It is highly conserved in vertebrates and most abundantly expressed in the brain

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a proteinLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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