Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels There are numerous pseudogenes of

There are numerous pseudogenes of this gene distributed throughout the genome

The protein encoded by this gene is a member of the tripartite motif (TRIM) family

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Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling

Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels There are numerous pseudogenes ofThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.