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MED22 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The encoded protein forms a

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MED22 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The encoded protein forms aThis gene encodes a protein component of the mediator complex, which functions in the regulation of transcription by bridging interactions between gene specific regulatory factors, RNA polymerase II, and general transcription factors. Alternatively spliced transcript variants encoding different isoforms have been observed.

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Description

The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4)

also known as Stargardt Disease

The expression of variant 1 is suppressed in many tumor cell lines

This protein possesses 3' to 5' exonuclease activity

It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP

MED22 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The encoded protein forms aThis gene encodes a protein component of the mediator complex, which functions in the regulation of transcription by bridging interactions between gene specific regulatory factors, RNA polymerase II, and general transcription factors. Alternatively spliced transcript variants encoding different isoforms have been observed.

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