IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks protein homology

protein homology

Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported| one of which is a nonsense-mediated decay candidate

but its biological validity has not been determined

The tumor protein D52 (TPD52) family consists of three members

guinea pig

IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks protein homologyIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms