UBF(Phospho Ser484) Polyclonal Antibody, 50ul Insect Expression Gene expression is high during

Gene expression is high during fetal development and in most tumors| yet low in adult tissues

Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes

May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons

and negatively regulate NTR induced cell death and NF-kappa B activation

which regulate the release of neurotransmitters

UBF(Phospho Ser484) Polyclonal Antibody, 50ul Insect Expression Gene expression is high duringThis gene encodes a member of the HMG box DNA binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively