Chk2(Phospho Ser516) Polyclonal Antibody, 100ul Endonucleases & Exonucleases Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 encoded by ENPP2 functions as both a phosphodiesterase

Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency

the basic N-terminus is highly homologous to the N-terminus of a related gene

The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin)

This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate

Chk2(Phospho Ser516) Polyclonal Antibody, 100ul Endonucleases & Exonucleases Ectonucleotide pyrophosphatase/phosphodiesterase family member 2In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the