Chordin Polyclonal Antibody, 50ul Measuring Instruments Alternative splicing of this gene

Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms

induction:By HBxAg

and methylates DNA polymerase beta

Amplification and/or overexpression of this gene has been reported in numerous cancers

The protein encoded by this gene contains a GTPase-activating protein domain

Chordin Polyclonal Antibody, 50ul Measuring Instruments Alternative splicing of this geneThis gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF beta like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration.