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Epsin 2 Polyclonal Antibody, 50ul Drying & Desiccation Since the N-terminal 147 amino

SKU: 32451870599

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Epsin 2 Polyclonal Antibody, 50ul Drying & Desiccation Since the N-terminal 147 aminoEPN2 encodes a protein which interacts with clathrin and adaptor related protein complex 2, alpha 1 subunit. Epsin 2 is found in a brain derived clathrin coated vesicle fraction and localizes to the peri Golgi region and the cell periphery. The protein is thought to be involved in clathrin mediated endocytosis. Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms

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Description

Since the N-terminal 147 amino acid residues of GAL4 are sufficient to mediate specific and strong binding to DNA

some members of which are clustered together on chromosome 12q13

This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene

as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs)

It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A)

Epsin 2 Polyclonal Antibody, 50ul Drying & Desiccation Since the N-terminal 147 aminoEPN2 encodes a protein which interacts with clathrin and adaptor related protein complex 2, alpha 1 subunit. Epsin 2 is found in a brain derived clathrin coated vesicle fraction and localizes to the peri Golgi region and the cell periphery. The protein is thought to be involved in clathrin mediated endocytosis. Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms

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