MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture The predominant isoform

The predominant isoform

It specifically interacts with TNFRSF9/4-1BB| a member of the tumor necrosis factor receptor (TNFR) superfamily

Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

This protein may be involved in the onset of pain associated with peripheral neuropathy

MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture The predominant isoformThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and