p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Transcription factor E2F4 encoded by

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases

This gene is clustered with other MAGED genes on chromosome Xp11

function:Receptor for members of the ephrin-A family

2001 [PubMed 11242035])

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Transcription factor E2F4 encoded byTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni