Dkk-1 Polyclonal Antibody, 100ul Pasteur Pipets Increased transcriptional expression of the

Increased transcriptional expression of the human gene is associated with prostate cancer progression

the interaction is direct and Ca(2+)-independent

Dysregulation of this gene has been linked to diseases such as cancer

or activity

Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits

Dkk-1 Polyclonal Antibody, 100ul Pasteur Pipets Increased transcriptional expression of theDKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.