TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification The gene product is thought

The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway

cell signaling survival

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex

It is an orphan receptor

Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease

TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification The gene product is thoughtTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,