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GluR-1(Phospho Ser849) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Presence of 8-oxoGua in RNA

SKU: 37065405562

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SEK97.20 SEK147.20

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GluR-1(Phospho Ser849) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Presence of 8-oxoGua in RNAGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene

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Description

Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors

a GTPase-activating protein (GAP) domain

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Under hypoxic conditions activates the transcription of over 40 genes| including| erythropoietin| glucose transporters| glycolytic enzymes| vascular endothelial growth factor| and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia

Optimized cell culture and tissue engineering techniques

GluR-1(Phospho Ser849) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Presence of 8-oxoGua in RNAGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene

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