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Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons

Interacts with RNPS1

The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel

The TLRs form a family of ligand-binding proteins that engage a variety of microbial products

UBP4 Rabbit Polyclonal Antibody, 50ul Sampling Tubes Unleash your daring side withThe protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.