Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The protein encoded by PKN1

The protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily

The syndecan 1 encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family

This gene is present in a gene cluster with other members of the ADAM family on chromosome 8

Accumulation of EXPAND1/MUM1 at damaged DNA sites is thought to modify the structure of the chromatin and allow access to other DNA repair factors

many of which may be expressed only in tumor cells

Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The protein encoded by PKN1Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which