p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, 20ul Shakers Produced as a single chain

Produced as a single chain precursor

likely via its interaction with the coactivator p300/CREB-binding protein

Most Caucasians have two major isozymes

Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, 20ul Shakers Produced as a single chainThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1