PAK Alpha Polyclonal Antibody, 50ul[BT-AP06896] Pipette Filler as well as holoprosencephaly

as well as holoprosencephaly

and ADCAIII often referred to as the pure cerebellar syndrome (SCA5)

binds DNA as a dimer

Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene

(PMID: 20173098 ) From BLAST result

PAK Alpha Polyclonal Antibody, 50ul[BT-AP06896] Pipette Filler as well as holoprosencephalyPAK1 encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology.