WIT1 Polyclonal Antibody, 50ul Primary Antibodies This gene encodes a cytokine

This gene encodes a cytokine that belongs to the interferon family of signaling proteins| which are released as part of the innate immune response to pathogens

Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes

These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures

whose activity is required for cell cycle G1/S transition

the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway

WIT1 Polyclonal Antibody, 50ul Primary Antibodies This gene encodes a cytokineThis gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis.