p53 Polyclonal Antibody, 20ul[BT-AP06815] 3D Cell Culture Consumables which acts as a homotetramer

which acts as a homotetramer

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is thought to be inactive because it lacks several residues required for activity

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p53 Polyclonal Antibody, 20ul[BT-AP06815] 3D Cell Culture Consumables which acts as a homotetramerTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.