Islet-1 Monoclonal Antibody, 100ul[BT-MCA0789] Recombinant Protein Expression a progressive demyelination disease which

a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death

KCNK17 is activated at alkaline pH

This gene is one of a cluster of highly related genes located at chromosomal region 19q13

The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates

Inhibits the transcriptional activation mediated by PAX5

Islet-1 Monoclonal Antibody, 100ul[BT-MCA0789] Recombinant Protein Expression a progressive demyelination disease whichThis gene encodes a member of the LIM homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity onset diabetes of the young.