BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Phosphorylation at Ser-425 and Ser-428

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

Inhibitors of the encoded protein may be effective in treating congestive heart failure

Diseases associated with GLB1L3 include leber congenital amaurosis

The protein may be involved in transduction of high-temperature heat responses in sensory ganglia

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Phosphorylation at Ser-425 and Ser-428BRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal