Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression Two transcript variants encoding different

Two transcript variants encoding different isoforms have been found for PLCG1

An important paralog of this gene is ERAP2

This gene was identified by the interaction of its gene product with Grap2

HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts

Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders

Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression Two transcript variants encoding differentThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.