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I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis this gene is not a

SKU: 53564990169

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I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis this gene is not aThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

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Description

this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins

Alternatively-spliced transcript variants have been observed

The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis

Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration

this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation

I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis this gene is not aThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

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