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HoxD8 Polyclonal Antibody, 50ul Cell Biology May interacts with MAVS/IPS1

SKU: 53983684072

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HoxD8 Polyclonal Antibody, 50ul Cell Biology May interacts with MAVS/IPS1HOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions

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Description

May interacts with MAVS/IPS1

and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA

Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II

Has a two domain structure: the G-domain binds GTP

HoxD8 Polyclonal Antibody, 50ul Cell Biology May interacts with MAVS/IPS1HOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions

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