dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Suppressor of cytokine signaling 2

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

Mutations in this gene are associated with X-linked Alport syndrome

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a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis

Phosphorylated by ATR upon DNA damage

dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Suppressor of cytokine signaling 2Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle