Dnmt3b Polyclonal Antibody, 50ul Filtration with cadherin domains acting as
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Dnmt3b Polyclonal Antibody, 50ul Filtration with cadherin domains acting asCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated.
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