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DBLOH Polyclonal Antibody, 50ul Filtration Alternative translation initiation site usage

SKU: 5969892054

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DBLOH Polyclonal Antibody, 50ul Filtration Alternative translation initiation site usageThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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Description

Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216)

DZIP3 (DAZ Interacting Zinc Finger Protein 3) is a Protein Coding gene

The peptide binding cleft accommodates peptides of 10-30 residues

Molecular diagnosis involves using nucleic acids or proteins as biomarkers to help diagnose and treat diseases more effectively

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DBLOH Polyclonal Antibody, 50ul Filtration Alternative translation initiation site usageThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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