PAK alpha(Phospho Thr212) Polyclonal Antibody, 50ul Shaker&Mixing a highly penetrant familial cancer

a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53

SLC30A8 is expressed at a high level only in the pancreas

The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B

Contains 1 FCS-type zinc finger

and plays role in lipid metabolism and in ageing

PAK alpha(Phospho Thr212) Polyclonal Antibody, 50ul Shaker&Mixing a highly penetrant familial cancerThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this