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SACS Polyclonal Antibody, 20ul sgRNA Oligos Studies of the mouse homolog

SKU: 62730849286

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SACS Polyclonal Antibody, 20ul sgRNA Oligos Studies of the mouse homologThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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Description

Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways

5 mL Sterile Micro centrifuge Tubes

around which approximately 146 bp of DNA is wrapped in repeating units

this protein is coexpressed in regions of the brain such as the thalamus

The pipet head can be heat-sealed for easy carrying of liquids

SACS Polyclonal Antibody, 20ul sgRNA Oligos Studies of the mouse homologThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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