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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets This gene belongs to the

SKU: 63330269147

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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets This gene belongs to theThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen

Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms

The mediator complex subunit 8 may also function in ubiquitin ligation and protein degradation

EI2BE Polyclonal Antibody, 100ul Pasteur Pipets This gene belongs to theThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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