LTOR3 Polyclonal Antibody, 20ul Microbial Genome Editing down-regulated by phorbol 12-myristate 13-acetate

down-regulated by phorbol 12-myristate 13-acetate

|Contains 7 ANK repeats

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection| tissue damage| or stress| by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein

The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop

Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum

LTOR3 Polyclonal Antibody, 20ul Microbial Genome Editing down-regulated by phorbol 12-myristate 13-acetateThis gene encodes a scaffold protein that functions in the extracellular signal regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen activated protein binding protein interacting protein, and binds specifically to MAP kinase kinase MAP2K1 MEK1, MAP kinase MAPK3 ERK1, and MAP kinase MAPK1 ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.