AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases SH3RF3 (SH3 Domain Containing Ring

SH3RF3 (SH3 Domain Containing Ring Finger 3) is a Protein Coding gene

This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2

The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex

Two related pseudogenes have been identified on chromosome 16

MAP kinases act as an integration point for multiple biochemical signals

AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases SH3RF3 (SH3 Domain Containing RingThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for