S5A2 Polyclonal Antibody, 100ul Antibody Humanization Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding multiple isoforms have been observed for DHPS

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized

Mutations in this gene result in colobomata

This gene is expressed predominantly in the pancreas and is activated at alkaline pH

miscellaneous:'Reprimo' signifies stop/repress

S5A2 Polyclonal Antibody, 100ul Antibody Humanization Alternatively spliced transcript variants encodingThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).